background: identification of regional pattern of poisoning is essential for health care authorities for proper planning on prevention programs and optimized management of antidote stockpiles. this study was designed to evaluate one-year epidemiologic pattern of acute poisoning cases treated at a tertiary care hospital in thrissur, india. methods: in this retrospective cross sectional study, me...

background:the pattern of poisoning has a regional variability. this study was carried out to describe the epidemiological profile of acute poisoning in northeastern bangladesh and to evaluate the mortality. methods:in this retrospective cross-sectional study, medical records of poisoned patients treated at department of medicine of sylhet m.a.g. osmani medical college hospital, sylhet, banglad...

BACKGROUND Although human embryonic stem cells (hESCs) hold great promise as a source of differentiated cells to treat several human diseases, many obstacles still need to be surmounted before this can become a reality. First among these, a robust chemically-defined system to expand hESCs in culture is still unavailable despite recent advances in the understanding of factors controlling hESC se...

background: the term caustic generally refers to alkaline and the term corrosive generally refers to acidic agents' injury however, in medical literature caustic is frequently a term applied to both substances. ingested alkali typically damage the esophagus more than stomach or duodenum, whereas acids usually cause more severe gastric injury. since esophagus has a slightly alkaline ph, its...

Cardiomyocytes (CMs) derived from human embryonic stem cells (hESCs) or human induced pluripotent stem cells (hiPSCs) are functionally heterogeneous, display insufficient biological efficacy and generally possess the electrophysiological properties seen in fetal CMs. However, a homogenous population of hESC/hiPSC-CMs, with properties similar to those of adult human ventricular cells, is require...

Syzygium cumini is a medicinal plant traditionally used to treat cardiometabolic disorders. This study proposed evaluate the cardiopreventive effect of hydroalcoholic extract from S. leaves (HESc) on ischemic injury isoproterenol (ISO)-induced in rats. Male albino Wistar rats (Rattus norvegicus) were pre-treated with HESc or water for 15 days. They received challenge ISO (85 mg/kg) 14th and 15t...

Colloidal chemically converted graphene sheets (CCGs) are able to contact with each other to form stable self-assembled stacked-CCGs via salt "invasion", which can serve as powerful building blocks for capturing double-stranded DNA.

Cardiosphere-derived cells (CDCs) have emerged as one of the most promising stem cell types for cardiac protection and repair. Exosomes are required for the regenerative effects of human CDCs and mimic the cardioprotective benefits of CDCs such as anti-apoptotic effect in animal myocardial infarction (MI) models. Here we aimed to investigate the anti-apoptotic effect of the hypoxic and normoxic...

in spite of serious cardiotoxicity side-effects, doxorubicin is frequently used for treatment of several types of cancers. isolated human adult cardiomyocytes could be the best model for assessing drug-induced cardiotoxicity, while harvesting mature cardiomyocytes is restricted by some limitations such as biopsy size, cell numbers, viability, proliferative capacity and their disability to be pa...

Two types of graphene nanoribbons: (a) potassium-split graphene nanoribbons (GNRs), and (b) oxidative unzipped and chemically converted graphene nanoribbons (CCGNRs) were investigated for their magnetic properties using the combination of static magnetization and electron spin resonance measurements. The two types of ribbons possess remarkably different magnetic properties. While a low-temperat...